"A rich historical pastiche of 17th- and 18th-century philosophy, science, and religion."—G. Y. Craig, New Scientist "This book, by a distinguished Italian historian of philosophy, is a worthy successor to the author's important works on Francis Bacon and on technology and the arts. First published in Italian (in 1979), it now makes available to English readers some subtly wrought arguments about the ways in which geology and anthropology challenged biblical chronology and forced changes in the philosophy of history in the (...) early modern era.... [Rossi] shows that the search for new answers about human origins spanned many disciplines and involved many fascinating intellects—Bacon, Bayle, Buffon, Burnet, Descartes, Hobbes, Holbach, Hooke, Hume, Hutton, Leibniz, de Maillet, Newton, Pufendorf, Spinoza, Toland, and, most especially, Vico, whose works are impressively and freshly reevaluated here."—Nina Gelbart, American Scientist. (shrink)

A syncretic yogic instruction in Carakasanhita : Śārīrasthāna 1.137–155, contained in Book 4 of the Ćarakasaṃhitā, is a short treatise on yoga presented for āyurvedic purposes. In its yogic interpretation, the work comprises the Upaniṣads, the Mahābhārata, some Sāṃkhya’s and Vaiśeṣika’s notions as well as the meditative interpretation present in the Buddhist tradition. The ŚS gives a threefold path leading to mokṣa, the state of supreme brahman with which the conscious being, bhūtātman, becomes one : yoga, smṛti, and sāṃkhya. The (...) path to liberation is based on yoga, which is the reinforcement of the manas in the ātman and the stopping of suffering by breaking the connection between the erroneous identification of ātman with manas and the senses. On the path of yoga, a powerful eight-fold magical power is created through which the yogi is able to overcome external adversities. In the next step, the recognition of the one’s true identity — according to the sāṃkhya — is made through buddhi by the power of jñāna. However, in order for this recognition to be realized, the state of purity of sattva must first appear, induced by the practice of the eight-step smṛti realized by eighteen perfections. (shrink)

As guidelines for neonatal resuscitation evolve from a growing evidence base, clinicians must ensure that practice is closely aligned with the available evidence, based on methodologically sound and ethically conducted research. This paper reviews ethical, legal and risk-management issues arising during the design of a quality-assurance project to make video recordings of neonatal resuscitations after high-risk deliveries. The issues, which affect patients, researchers, staff and the hospital at large, include the following: 1) Informed consent for research involving emergency procedures is (...) often not possible, for lack of time to provide sufficient information. The mental capacity of the subject or parent may be compromised by the impending emergency, and freedom of choice is threatened by the time pressure to consent. 2) Video recording of the inevitable medical errors raises issues of whether participating staff may be identifiable and accountable, affecting their willingness to participate in such research. The approach to staff participation and identification is reviewed. 3) The use of video data for education threatens the privacy of research subjects. The ethics of maintaining privacy is balanced with the ethics of using the data to improve practice of resuscitation. 4) The research subjects (patients, or the staff whose performance is being monitored) must be defined. 5) There are legal and ethical aspects of management and ownership of data. 6) The role of the Human Research Ethics Committee in protecting the research subject and possibly the medicolegal interests of the hospital is discussed. This paper reviews the literature and discusses the issues. (shrink)

The mammalian centromere is a multifunctional chromosomal domain with a complexity that is reflected in its higher order structure, DNA sequence organization and protein composition. The centromere plays a major role during cell division where it functions as the site for the integration of the chromosome with the mitotic spindle, the site of the mechanochemical motor responsible for the movement of chromosomes and the major and last point of interaction between sister chromatids. Recent studies have focused on characterizing the components (...) of the centromere and establishing their relationship to its function. The following brief review summarizes some selected aspects of this recent work. (shrink)

Many organisms face a dilemma rooted in the unequal numbers of X chromosomes carried by the two sexes and the need to maintain equivalent expression of X‐linked genes. Several strategies have arisen to cope with this problem. All rely on accurately targeting epigenetic modifications to entire chromosomes. Targeting results from the action of recognition elements that attract modification and may rely on spreading of modification in cis along the affected chromosome. A recent report describing the first X chromosome recognition element (...) from C. elegans opens the way to defining the relative contributions of these factors to the compensation of X‐linked gene expression in worms.1 Extrachromosomal arrays composed of a C. elegans recognition element attract proteins that modify the C. elegans X chromosomes and interact genetically with mutations disrupting compensation. Moreover, examination of X:A translocations provides the first evidence for spreading of modification along C. elegans X chromosomes. BioEssays 26:707–710, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

ObjectiveBreast cancer may profoundly affect a couple’s sex life. The present study examines whether patient-, partner- and relationship-related characteristics are associated with sexual activity of couples following breast cancer diagnosis in the treatment phase and over time.MethodsWomen with breast cancer and their male cohabiting partners participated in a longitudinal study in Denmark. Logistic regression was used to examine associations of patient-, partner- and relationship-related characteristics at baseline with couples’ sexual activity at baseline, 5 and 12 months later. The longitudinal analyses (...) were stratified for couples’ sexual activity status at baseline.ResultsA total of 722, 533 and 471 couples were included in the analyses at baseline, 5- and 12-months follow-up, respectively. Older age, depressive symptoms and lower vitality of patients were associated with lower odds of couples’ sexual activity at baseline; chemotherapy treatment and older age of patients were associated with lower odds at 5-months follow-up in couples who were not sexually active at baseline. Higher ratings of emotional closeness, affectionate behavior and satisfaction with dyadic coping were associated with higher odds for sexual activity at baseline and over time in couples who were sexually active at baseline.ConclusionSexual counseling during cancer treatment and rehabilitation should include a couple perspective. Relationship-related variables may be a protective factor for remaining sexually active after breast cancer diagnosis. Interventions could focus on strengthening these factors. Health professionals also need to consider the patients’ breast cancer treatment, vitality, and emotional distress in counselling on sexuality. (shrink)

I argue against the common and influential view that non-trivial chances arise only when the fundamental laws are indeterministic. The problem with this view, I claim, is not that it conflicts with some antecedently plausible metaphysics of chance or that it fails to capture our everyday use of ‘chance’ and related terms, but rather that it is unstable. Any reason for adopting the position that non-trivial chances arise only when the fundamental laws are indeterministic is also a reason for adopting (...) a much stronger, and far less attractive, position. I suggest an alternative account, according to which chances are probabilities that play a certain explanatory role: they are probabilities that explain associated frequencies. (shrink)

It is divided into four sections covering science as a whole, the new technologies of the postmodern era, bio-medical discourses, and nature. A distinguished cast of contributors explores the central feminist concerns in each arena, through the central metaphors of monster, mother goddess and cyborg. They look at the consequences of gynogenesis, postmodern eco-buddhism in heathcare, sexual violence in cyberspace, the postmodernization of menopause, the dolphin as androgyne and feminist environmentalism.

I argue against the common and influential view that non-trivial chances arise only when the fundamental laws are indeterministic. The problem with this view, I claim, is not that it conflicts with some antecedently plausible metaphysics of chance or that it fails to capture our everyday use of ‘chance’ and related terms, but rather that it is unstable. Any reason for adopting the position that non-trivial chances arise only when the fundamental laws are indeterministic is also a reason for adopting (...) a much stronger, and far less attractive, position. I suggest an alternative account, according to which chances are probabilities that play a certain explanatory role: they are probabilities that explain associated frequencies. 1 Introduction2 A Paradigm Case3 The Incompatibilist’s Criterion4 Against the Incompatibilist’s Criterion5 The Explanatory Criterion6 Conclusion. (shrink)

Much neuroethics literature concludes with a set of normative recommendations. While these recommendations can be a helpful way of summarizing a proposal for a future direction, some have recently argued that ethics scholarship has devoted insufficient attention to considerations of audience and real-world applications. To date, however, while scholars have conducted topic analyses of neuroethics literature, to our knowledge no study has evaluated who neuroethics scholarship addresses and what it recommends. The objective of the present study therefore was to provide (...) a preliminary characterization of recommendations offered in neuroethics scholarship and an assessment of their target audiences. Rather than attempting to demarcate what constitutes “neuroethics scholarship,” we analyzed text that authors’ had self-identified as being neuroethics-related: abstracts presented at the International Neuroethics Society (INS) annual meetings and published as top abstracts in AJOB Neuroscience in the last decade (2011–2020). We found that a majority of abstracts utilized conceptual methods (62.2%) and provided conceptual recommendations (68%). Roughly 77% of all abstracts did not explicitly address a target audience, yet nearly all of these were implicitly directed at other scholars. The remainder specified a target audience of scholars (12.2%), regulators (6.7%), healthcare providers (6.7%) and industry (2.6%). Only a subset of abstracts provided practical or policy recommendations (19.7%). Of those, the majority (61.5%) did not specify a target audience. Among the subset with actionable recommendations, a clarification of target audience may help increase the impact. (shrink)

This paper discusses the possibility of modelling inductive inference (Gold 1967) in dynamic epistemic logic (see e.g. van Ditmarsch et al. 2007). The general purpose is to propose a semantic basis for designing a modal logic for learning in the limit. First, we analyze a variety of epistemological notions involved in identification in the limit and match it with traditional epistemic and doxastic logic approaches. Then, we provide a comparison of learning by erasing (Lange et al. 1996) and iterated epistemic (...) update (Baltag and Moss 2004) as analyzed in dynamic epistemic logic. We show that finite identification can be modelled in dynamic epistemic logic, and that the elimination process of learning by erasing can be seen as iterated belief-revision modelled in dynamic doxastic logic. Finally, we propose viewing hypothesis spaces as temporal frames and discuss possible advantages of that perspective. (shrink)

Gutenbergs tryckteknik ledde till en medierevolution som förändrades Europa. I 1500-talets början spreds litteratur, grafik och vetenskap, men också nyhetsblad om katastrofer, pamfletter om invaderande turkar och religiösa stridsskrifter. Medan mycket ännu vägde blommade renässanshumanismen genom Erasmus av Rotterdam. Han stod bakom en femtedel av Europas böcker, och skulle ge framtiden ett viktigt arv. Nina Burton skriver om Erasmus och hans tid så att man känner sig vara med när han träffar konstnärerna och de intellektuella? Albrecht Dürer, Holbein d.y., (...) Paracelsus, Thomas More och Luther? lika väl som påvar, kejsare, pedagoger och rebeller. Genom honom möter man en hel epok. Vilken var Erasmus hemlighet? I sina brev klottrade han självporträtt med dubbla ansikten, och hans förmåga att se två sidor födde ett samtal bortom all fanatism? en dröm om ett gränslöst Europa, där kultur och vetenskap knöt nya samband. Men då religiösa strider började skaka världen fick han mäktiga fiender. Erasmus visade vilken roll litteraturen kan spela i en dramatisk tid som har många likheter med vår egen. (shrink)

A series of recent arguments purport to show that most counterfactuals of the form if A had happened then C would have happened are not true. These arguments pose a challenge to those of us who think that counterfactual discourse is a useful part of ordinary conversation, of philosophical reasoning, and of scientific inquiry. Either we find a way to revise the semantics for counterfactuals in order to avoid these arguments, or we find a way to ensure that the relevant (...) counterfactuals, while not true, are still assertible. I argue that regardless of which of these two strategies we choose, the natural ways of implementing these strategies all share a surprising consequence: they commit us to a particular metaphysical view about chance. (shrink)

Relational reasoning is a hallmark of human higher cognition and creativity, yet it is notoriously difficult to encourage in abstract tasks, even in adults. Generally, young children initially focus more on objects, but with age become more focused on relations. While prerequisite knowledge and cognitive resource maturation partially explains this pattern, here we propose a new facet important for children's relational reasoning development: a general orientation to relational information, or a relational mindset. We demonstrate that a relational mindset can be (...) elicited, even in 4‐year‐old children, yielding greater than expected spontaneous attention to relations. Children either generated or listened to an experimenter state the relationships between objects in a set of formal analogy problems, and then in a second task, selected object or relational matches according to their preference. Children tended to make object mappings, but those who generated relations on the first task selected relational matches more often on the second task, signaling that relational attention is malleable even in young children. (shrink)

A long tradition of psychological research has explored the distinction between characteristics that are part of the self and those that lie outside of it. Recently, a surge of research has begun examining a further distinction. Even among characteristics that are internal to the self, people pick out a subset as belonging to the true self. These factors are judged as making people who they really are, deep down. In this paper, we introduce the concept of the true self and (...) identify features that distinguish people’s understanding of the true self from their understanding of the self more generally. In particular, we consider recent findings that the true self is perceived as positive and moral, and that this tendency is actor-observer invariant and cross-culturally stable. We then explore possible explanations for these findings and discuss their implications for a variety of issues in psychology. (shrink)

Many authors assume that Broca's area subserves the functions that are lost in patients with Broca's aphasia. This commentary attempts to clarify the relationship between Broca's area and Broca's aphasia and suggests that statements about the neurology of patients' specific language functions might be better supported by their individual structural neuroimaging data.

This paper generalizes Muddy Children puzzle to account for a large class of possible public announcements with various quantifiers. We identify conditions for solvability of the extended puzzle, with its classical version as a particular case. The characterization suggests a novel way of modeling multi-agent epistemic reasoning. The framework is based on the concept of number triangle. The advantage of our approach over more general formalizations in epistemic logics, like Dynamic Epistemic Logic, is that it gives models of linear size (...) w.r.t. the number of agents. Therefore, it is computationally plausible for modeling agents’ internal perspective. (shrink)

Tree diagrams are the prevailing form of visualization in biological classification and phylogenetics. Already during the time of the so-called Systematist Wars from the mid-1960s until the 1980s most journal articles and textbooks published by systematists contained tree diagrams. Although this episode of systematics is well studied by historians and philosophers of biology, most analyses prioritize scientific theories over practices and tend to emphasize conflicting theoretical assumptions. In this article, I offer an alternative perspective by viewing the conflict through the (...) lens of representational practices with a case study on tree diagrams that were used by numerical taxonomists (phenograms) and cladists (cladograms). I argue that the current state of molecular phylogenetics should not be interpreted as the result of a competition of views within systematics. Instead, molecular phylogenetics arose independently of systematics and elements of cladistics and phenetics were integrated into the framework of molecular phylogenetics, facilitated by the compatibility of phenetic and cladistic practices with the quantitative approach of molecular phylogenetics. My study suggests that this episode of scientific change is more complex than common narratives of battles and winners or conflicts and compromises. Today, cladograms are still used and interpreted as specific types of molecular phylogenetic trees. While phenograms and cladograms represented different forms of knowledge during the time of the Systematist Wars, today they are both used to represent evolutionary relationships. This indicates that diagrams are versatile elements of scientific practice that can change their meaning, depending on the context of use within theoretical frameworks. (shrink)

The concept of intersectionality is on its way to becoming a new paradigm in gender studies. In its current version, it denominates reciprocities between gender, race and class. However, it also allows for the integration of other socially defined categories, such as sexuality, nationality or age. On the other hand, it is widely left unclear as to which level these reciprocal effects apply: the level of social structures, the level of constructions of identity or the level of symbolic representations. This (...) article advocates an intersectional multi-level analysis which takes into account reciprocal effects between the various levels. This approach includes an analytical grasp of and methodical reflection on these reciprocal effects as well as making them empirically accessible. (shrink)

I argue that there are such things as nomological probabilities—probabilities that play a certain explanatory role with respect to stable, long-run relative frequencies. Indeed, I argue, we should be willing to accept nomological probabilities even if they turn out to be metaphysically weird or even wholly sui generis entities. I then give an example of one way in which this argument should shape future work on the metaphysics of chance by describing a challenge to a common group of analyses of (...) objective probability—Humean analyses— understood as analyses of nomological probability. (shrink)

We discuss Hintikka’s Thesis [Hintikka 1973] that there exist natural language sentences which require non–linear quantification to express their logical form.

Student plagiarism is a rampant practice and major concern in higher education. How students perceive the overarching American cultural values and their impact on the practice will inform educators and help them to better combat the practice. It is also valuable for educators to know whether the students perceive the practice to be part of the dominant culture, currently, on college campuses. This study reports perceptions of plagiarism by students in an introductory sociology course. Open-ended questions explored perceptions of extent, (...) justifications, and American values affecting plagiarism. Participants were clear on definitions and seriousness, but most were able to justify the behavior and identify American values contributing to or deterring the practice. Findings were consistent across gender, course grade, class standing, and college major. The authors discuss the cultural values students use as justifications for plagiarizing and the larger implications for higher education. (shrink)

Experience has shown that the application of ethical guidelines developed for research in developed countries to research in developing countries can be, and often is, impractical and raises a number of contentious issues. Various attempts have been made to provide guidelines more appropriate to the developing world context; however, to date these efforts have been dominated by the fields of bioscience, medical research and nutrition. There is very little advice available for those seeking to undertake collaborative social science or natural (...) science research in developing countries and what is there tends to be held within disparate sources. Charting the development of a set of ethics documentation for future use by the Ecosystem Services for Poverty Alleviation (ESPA) programme research community, this paper outlines past and present attitudes towards ethics procedures amongst this community and suggests ways in which ethics procedures might be made more relevant and user-friendly to researchers working in this area. (shrink)

I argue that the way the world appears to be plays an important role in standard scientific practice, and that therefore the way the world appears to be ought to play a similar role in metaphysics as well. I then show how the argument bears on a specific first-order debate in metaphysics – the debate over whether there are composite objects. This debate is often thought to be a paradigm case of a metaphysical debate that is largely insulated from scientific (...) considerations, and is often disparaged or avoided by naturalistically inclined metaphysicians as a result. My argument below shows that this attitude is a mistake. The way in which metaphysical debates can be informed by our best science is more complex and far-reaching than is often acknowledged in the literature. (shrink)

Das Sterben wird längst nicht mehr verdrängt und verschwiegen, es gehört vielmehr zu den ausgiebig erörterten Themen unserer Zeit. Viele Debatten ranken sich um Sterbehilfe und um die Frage, was einen guten Tod ausmacht. Dabei scheinen wir uns bemerkenswert einig zu sein, dass gut stirbt, wer bis zuletzt er oder sie selbst bleibt. Wir wünschen uns, so die These dieses Buches, unseren 'eigenen Tod': ein Lebensende, wie es uns entspricht, ein authentisches Sterben. Dieses Ideal leitet in unterschiedlicher Weise die Palliativversorgung (...) und die Sterbehilfebewegung an. Doch Nina Streeck zeigt, dass sich das, was so erstrebenswert klingt, als anspruchsvoll entpuppt. Die Idee des 'eigenen Todes' droht sich in ihr Gegenteil zu verkehren: in einen Zwang zum authentischen Sterben."--Page 4 of cover. (shrink)

The paper is concerned with the psychological relevance of a logical model for deductive reasoning. We propose a new way to analyze logical reasoning in a deductive version of the Mastermind game implemented within a popular Dutch online educational learning system (Math Garden). Our main goal is to derive predictions about the difficulty of Deductive Mastermind tasks. By means of a logical analysis we derive the number of steps needed for solving these tasks (a proxy for working memory load). Our (...) model is based on the analytic tableaux method, known from proof theory. We associate the difficulty of Deductive Mastermind game-items with the size of the corresponding logical trees obtained by the tableaux method. We derive empirical hypotheses from this model. A large group of students (over 37 thousand children, 5–12 years of age) played the Deductive Mastermind game, which gave empirical difficulty ratings of all 321 game-items. The results show that our logical approach predicts these item ratings well, which supports the psychological relevance of our model. (shrink)

The article attempts to answer the question concerning the possibility of reinterpreting tapas and locating it in the risk society. The authors, referring to Ulrich Beck’s concept, look for the ways out of the “kingdom of shadows”, possessed by a constant sense of threat, both in the global and local sphere. The article takes a cross-sectional look at tapas in old Indian literature, looking for possibilities of its contemporary implementation on non-Indian grounds, as a response to the deteriorating psycho-physical state (...) of 21st century society. (shrink)

The relevance of the study is that the II Vatican Council has not only historical but also cultural significance for the believers. The ideology of the Ajornamento, introduced by this Council, is directed not only to dialogue and tolerance, the rapprochement and unity of the believers in the modern world, but also to the revival of the names of those figures who, through their apostolic activity, have been ahead of their time for millenia and have become a model for modern (...) religious tradition. This implies the phenomenon of Cyril and Methodius - Slavic educators and apostles who, during missionary activities in Moravia and Pannonia, initiated the Slavic rite of Christianity and thus demonstrated the example of the first Christian inculturation. (shrink)